[4-AMINO-2-(4-CHLOROANILINO)-1,3-THIAZOL-5-YL](4-CHLOROPHENYL)METHANONE

Base Information

• Chemical Name: [4-AMINO-2-(4-CHLOROANILINO)-1,3-THIAZOL-5-YL](4-CHLOROPHENYL)METHANONE
• CAS No.: 107401-72-9
• Molecular Formula: C₁₆H₁₁Cl₂N₃OS
• Molecular Weight: 364.255
• Mol file: 107401-72-9.mol

Synonyms:[4-amino-2-(4-chlorophenylamino)thiazol-5-yl](4-chlorophenyl)methanone

Chemical Property of [4-AMINO-2-(4-CHLOROANILINO)-1,3-THIAZOL-5-YL](4-CHLOROPHENYL)METHANONE

Chemical Property:

Purity/Quality:

[4-AMINO-2-(4-CHLOROANILINO)-1,3-THIAZOL-5-YL](4-CHLOROPHENYL)METHANONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [4-AMINO-2-(4-CHLOROANILINO)-1,3-THIAZOL-5-YL](4-CHLOROPHENYL)METHANONE

There total 6 articles about [4-AMINO-2-(4-CHLOROANILINO)-1,3-THIAZOL-5-YL](4-CHLOROPHENYL)METHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.72%

→ [4-amino-2-(4-chlorophenylamino)thiazol-5-yl](4-chlorophenyl)methanone (107401-72-9)

Guidance literature:

Reference yield:

4-chlorobenzoylmethyl bromide (536-38-9) + 1-(4-chlorophenyl-3-(N-nitroguanidine))thiourea → [4-amino-2-(4-chlorophenylamino)thiazol-5-yl](4-chlorophenyl)methanone (107401-72-9)

Guidance literature:

With triethylamine; In dimethyl sulfoxide;

DOI:10.1016/j.tetlet.2012.05.010

Reference yield:

C16H14Cl2N4OS*BrH → [4-amino-2-(4-chlorophenylamino)thiazol-5-yl](4-chlorophenyl)methanone (107401-72-9)

Guidance literature:

With triethylamine; In ethanol; acetone; Yield given; 60 deg C; r.t., 1 h;

DOI:10.1055/s-1986-31634

upstream raw materials:

1-p-chlorophenyl-3-formamidinothiocarbamide

4-chlorobenzoylmethyl bromide

4-Chlorophenyl isothiocyanate

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