Chemical Property of 2-[1-(Diaminomethylidenehydrazinylidene)propan-2-ylideneamino]guanidine;dihydrochloride
Chemical Property:
- Melting Point:256 °C (decomp)
- Boiling Point:436.6oC at 760 mmHg
- Flash Point:217.8oC
- PSA：148.52000
- LogP:1.49810
- Storage Temp.:-20°
- Solubility.:Soluble in Water (greater than 25 mg/ml).
- Hydrogen Bond Donor Count:6
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:3
- Exact Mass:256.0718479
- Heavy Atom Count:15
- Complexity:264
- Purity/Quality:
-
99% *data from raw suppliers
MITOGUAZONE DIHYDROCHLORIDE 95.00% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC(=NN=C(N)N)C=NN=C(N)N.Cl.Cl
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Description
Mitoguazone (7059-23-6) is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC).1,2?SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in polyamine metabolism.3?Mitoguazone has also been shown to inhibit diamine oxidase and induce spermidine/spermine N-acetyltransferase.4,5 Mitoguazone has been looked at as a potential anti-cancer treatment because of its ability to inhibit polyamine synthesis.6
