2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Base Information

• Chemical Name: 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
• CAS No.: 1334297-40-3
• Molecular Formula: C₁₉H₂₀ClN₃O₆
• Molecular Weight: 421.837
• Mol file: 1334297-40-3.mol

Synonyms:2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Chemical Property of 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

There total 15 articles about 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C51H52ClN3O10 → 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (1334297-40-3)

Guidance literature:

C₅₁H₅₂ClN₃O₁₀; With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; dichloromethane; chloroform; water; at 20 ℃; for 3h;

With sodium hydrogencarbonate; In dichloromethane; water;

Reference yield:

C27H28ClN3O10 (1334297-39-0) → 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (1334297-40-3)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃; for 18h;

DOI:10.1016/j.bmc.2014.04.036

Reference yield:

(3R,4R,5R,6S)-2-(acetoxymethyl)-6-(4-chloro-3-((3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)methyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate → 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (1334297-40-3)

Guidance literature:

With methanol; potassium carbonate; at 20 ℃; for 18h;

upstream raw materials:

[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

(5-bromo-2-chlorobenzyloxy)(tert-butyl)diphenylsilane

C₃₇H₄₃ClO₁₀Si

C₂₇H₂₈ClN₃O₁₀