C₁₉H₂₁NO

Base Information

• Chemical Name: C₁₉H₂₁NO
• CAS No.: 1620403-94-2
• Molecular Formula: C₁₉H₂₁NO
• Molecular Weight: 279.382
• Mol file: 1620403-94-2.mol

Synonyms:C₁₉H₂₁NO

Chemical Property of C₁₉H₂₁NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₂₁NO

There total 7 articles about C₁₉H₂₁NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pent-1-yn-5-ol (5390-04-5) → C19H21NO (1620403-94-2)

Guidance literature:

Multi-step reaction with 6 steps

1.1: piperidine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / toluene / 2 h / 20 °C

2.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C

3.1: zinc; acetic acid / dichloromethane / 0 °C

4.1: triethylamine / tetrahydrofuran / 0 °C

5.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h

5.2: 20 °C

6.1: potassium hydroxide; water / Heating

With piperidine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; di-isopropyl azodicarboxylate; water; sodium hydride; acetic acid; triethylamine; triphenylphosphine; potassium hydroxide; zinc; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1021/ol501599j

Reference yield:

4-tolyl iodide (624-31-7) → C19H21NO (1620403-94-2)

Guidance literature:

Multi-step reaction with 6 steps

1.1: piperidine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / toluene / 2 h / 20 °C

2.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C

3.1: zinc; acetic acid / dichloromethane / 0 °C

4.1: triethylamine / tetrahydrofuran / 0 °C

5.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h

5.2: 20 °C

6.1: potassium hydroxide; water / Heating

With piperidine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; di-isopropyl azodicarboxylate; water; sodium hydride; acetic acid; triethylamine; triphenylphosphine; potassium hydroxide; zinc; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1021/ol501599j

Reference yield:

C20H21NO2 (1620403-71-5) → C19H21NO (1620403-94-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h

1.2: 20 °C

2.1: potassium hydroxide; water / Heating

With water; sodium hydride; potassium hydroxide; In N,N-dimethyl-formamide;

DOI:10.1021/ol501599j

upstream raw materials:

C₂₁H₂₃NO₂

pent-1-yn-5-ol

4-tolyl iodide

C₂₀H₂₁NO₂

Downstream raw materials:

C₁₉H₂₀N₂O₂

C₁₉H₁₉NO