1H-Indole-3-carboxylic acid, 5-((diethylamino)sulfonyl)-

Base Information

Chemical Name:1H-Indole-3-carboxylic acid, 5-((diethylamino)sulfonyl)-
CAS No.:120729-94-4
Molecular Formula:C₁₃H₁₆N₂O₄S
Molecular Weight:296.347
Hs Code.:
DSSTox Substance ID:DTXSID40152991
Wikidata:Q83019793
Mol file:120729-94-4.mol

Synonyms:120729-94-4;1H-Indole-3-carboxylic acid, 5-((diethylamino)sulfonyl)-;5-(diethylsulfamoyl)-1H-indole-3-carboxylic acid;5-(N,N-Diethylsulfamoyl)-1H-indole-3-carboxylic acid;BRN 3561051;5-((Diethylamino)sulfonyl)-1H-indole-3-carboxylic acid;Cambridge id 5242810;Oprea1_672898;DTXSID40152991;AB00076439-01;SR-01000200555;SR-01000200555-1

Suppliers and Price of 1H-Indole-3-carboxylic acid, 5-((diethylamino)sulfonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1H-Indole-3-carboxylic acid, 5-((diethylamino)sulfonyl)-

Chemical Property:

Vapor Pressure:7.06E-13mmHg at 25°C
Boiling Point:548.8°C at 760 mmHg
Flash Point:285.7°C
Density:1.391g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:296.08307817
Heavy Atom Count:20
Complexity:456

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)S(=O)(=O)C1=CC2=C(C=C1)NC=C2C(=O)O

Technology Process of 1H-Indole-3-carboxylic acid, 5-((diethylamino)sulfonyl)-

There total 3 articles about 1H-Indole-3-carboxylic acid, 5-((diethylamino)sulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.1%

: 120729-85-3
3-Formyl-1H-indole-5-sulfonic acid diethylamide

: 120729-94-4
5-Diethylsulfamoyl-1H-indole-3-carboxylic acid

Guidance literature:: With potassium permanganate; In water; acetone; at 30 - 35 ℃; for 2h;
DOI:10.1007/BF00764459

Reference yield:

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 120729-94-4
5-Diethylsulfamoyl-1H-indole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / chlorosulfonic acid / 2 h / 70 °C

2: 61.4 percent / H₂O; tetrahydrofuran / 30 - 35 °C

3: 50.1 percent / potassium permanganate / acetone; H₂O / 2 h / 30 - 35 °C

With chlorosulfonic acid; potassium permanganate; In tetrahydrofuran; water; acetone;
DOI:10.1007/BF00764459

Reference yield:

: 120768-89-0
5-chlorosulfonyl-3-formylindole

: 120729-94-4
5-Diethylsulfamoyl-1H-indole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 61.4 percent / H₂O; tetrahydrofuran / 30 - 35 °C

2: 50.1 percent / potassium permanganate / acetone; H₂O / 2 h / 30 - 35 °C

With potassium permanganate; In tetrahydrofuran; water; acetone;
DOI:10.1007/BF00764459