[S,(+)]-4,6-Dihydro-8-hydroxy-6-oxo-3-pentyl-3H-2-benzopyran-7-carboxylic acid

Base Information

Chemical Name:[S,(+)]-4,6-Dihydro-8-hydroxy-6-oxo-3-pentyl-3H-2-benzopyran-7-carboxylic acid
CAS No.:7681-94-9
Molecular Formula:C₁₅H₁₈O₅
Molecular Weight:278.305
Hs Code.:
Mol file:7681-94-9.mol

Synonyms:(R)-4,6-Dihydro-8-hydroxy-6-oxo-3-pentyl-3H-2-benzopyran-7-carboxylic acid;3H-2-Benzopyran-7-carboxylic acid,4,6-dihydro-8-hydroxy-6-oxo-3-pentyl-,(R);

Suppliers and Price of [S,(+)]-4,6-Dihydro-8-hydroxy-6-oxo-3-pentyl-3H-2-benzopyran-7-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of [S,(+)]-4,6-Dihydro-8-hydroxy-6-oxo-3-pentyl-3H-2-benzopyran-7-carboxylic acid

Chemical Property:

PSA：83.83000
LogP:2.64530

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [S,(+)]-4,6-Dihydro-8-hydroxy-6-oxo-3-pentyl-3H-2-benzopyran-7-carboxylic acid

There total 11 articles about [S,(+)]-4,6-Dihydro-8-hydroxy-6-oxo-3-pentyl-3H-2-benzopyran-7-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 186774-97-0
(+/-)-2,6-dihydroxy-4-(2-hydroxyheptyl)benzoic acid

: 122-51-0
orthoformic acid triethyl ester

: 21668-94-0,7681-94-9
(+/-)-pulvilloric acid

Guidance literature:: for 0.25h; Ambient temperature;

Reference yield: 56.0%

: 122-51-0
orthoformic acid triethyl ester

: 15601-13-5
(S)-(+)-2,6-dihydroxy-4-(2-hydroxyheptyl)benzoic acid

: 186820-80-4,7681-94-9
(S)-(-)-pulvilloric acid

Guidance literature:: for 0.25h; Ambient temperature;

Reference yield:

: 5063-65-0
1,2-epoxyheptane

: 21668-94-0,7681-94-9
(+/-)-pulvilloric acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) Mg, (CH₂Br)2, 2.) 1,5-cyclooctadienecopper(I) chloride / 1.) THF, reflux, 1.5 h, 2.) -33 deg C, 20 min; r.t., 12 h

2: 93 percent / H₂ / 5percent Pd/C / methanol; acetic acid / 10 h / 750.06 Torr

3: 56 percent / KHCO₃ / glycerol / 5 h / 145 - 150 °C / 750.06 Torr

4: 58 percent / 0.25 h / Ambient temperature

With hydrogen; potassium hydrogencarbonate; magnesium; ethylene dibromide; palladium on activated charcoal; In methanol; acetic acid; glycerol;