Erythronolide B

Base Information Edit

Chemical Name:Erythronolide B
CAS No.:3225-82-9
Molecular Formula:C₂₁H₃₈O₇
Molecular Weight:402.529
Hs Code.:
UNII:H8F3GHM6EA
Nikkaji Number:J14.506H
Wikidata:Q27103435
Metabolomics Workbench ID:51540
Mol file:3225-82-9.mol

Synonyms:erythronolide B;erythronolide-B

Suppliers and Price of Erythronolide B

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 16 raw suppliers

Chemical Property of Erythronolide B Edit

Chemical Property:

Vapor Pressure:1.12E-15mmHg at 25°C
Boiling Point:576.2°Cat760mmHg
PKA:13.81±0.70(Predicted)
Flash Point:192.2°C
PSA：124.29000
Density:1.069g/cm³
LogP:1.29520
XLogP3:1.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:402.26175355
Heavy Atom Count:28
Complexity:551

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)O)C)O)(C)O)C)C)O)C
Isomeric SMILES:CC[C@@H]1[C@@H]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O)C)O)(C)O)C)C)O)C

Technology Process of Erythronolide B

There total 36 articles about Erythronolide B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 123107-83-5
3,5-O-benzylideneerythronolide B

: 3225-82-9,19270-26-9,24784-66-5
Erythronolide B

Guidance literature:: With acetic acid; at 50 ℃; for 3h;
DOI:10.1007/BF00953635

Reference yield:

: 56014-68-7,56085-63-3,114182-42-2
3,5-O-benzylidene-(9S)-dihydroerythronolide B

: 3225-82-9,19270-26-9,24784-66-5
Erythronolide B

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / PCC, molecular sieves (3 Angstroem) / CH₂Cl₂ / 0.5 h / 0 °C

2: 65 percent / 80 percent AcOH / 3 h / 50 °C

With 3 A molecular sieve; acetic acid; pyridinium chlorochromate; In dichloromethane;
DOI:10.1016/S0040-4020(01)81090-5

Reference yield:

: 114137-94-9
3,5-isopropylidene-9-11-O-(p-methoxybenzylidene)-9(S)-dihydroerythronolide B

: 3225-82-9,19270-26-9,24784-66-5
Erythronolide B

Guidance literature:: Multi-step reaction with 4 steps

1: 88 percent / TFA / acetonitrile; H₂O / 0.08 h / Ambient temperature

2: 48 percent / (+/-)-camphor-10-sulfonic acid / CH₂Cl₂ / 5.5 h / -10 °C

3: 71 percent / PCC, molecular sieves (3 Angstroem) / CH₂Cl₂ / 0.5 h / 0 °C

4: 65 percent / 80 percent AcOH / 3 h / 50 °C

With 3 A molecular sieve; camphor-10-sulfonic acid; acetic acid; pyridinium chlorochromate; trifluoroacetic acid; In dichloromethane; water; acetonitrile;
DOI:10.1016/S0040-4020(01)81090-5