Technology Process of C23H31N7O6
There total 8 articles about C23H31N7O6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 3h;
DOI:10.1021/ol201184b
- Guidance literature:
-
Multi-step reaction with 8 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2: iodine; silver trifluoroacetate / chloroform / 15 h / 20 °C
3: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 15 h / 20 °C
4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
5: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 20 °C
6: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
7: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 4 h / 20 °C
8: tetrabutyl ammonium fluoride / tetrahydrofuran; methanol / 3 h / 20 °C
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutyl ammonium fluoride; iodine; silver trifluoroacetate; potassium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; N,N-dimethyl-formamide;
3: Sonogashira coupling;
DOI:10.1021/ol201184b
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 4 h / 20 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran; methanol / 3 h / 20 °C
With
tetrabutyl ammonium fluoride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ol201184b