(2R,3S)-tert-butyl 2-(diphenylmethyleneamino)-3-(4-fluorophenyl)-5-oxo-5-phenylpentanoate

Base Information

Chemical Name:(2R,3S)-tert-butyl 2-(diphenylmethyleneamino)-3-(4-fluorophenyl)-5-oxo-5-phenylpentanoate
CAS No.:1268449-14-4
Molecular Formula:C₃₄H₃₂FNO₃
Molecular Weight:521.631
Hs Code.:

Synonyms:(2R,3S)-tert-butyl 2-(diphenylmethyleneamino)-3-(4-fluorophenyl)-5-oxo-5-phenylpentanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3S)-tert-butyl 2-(diphenylmethyleneamino)-3-(4-fluorophenyl)-5-oxo-5-phenylpentanoate

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Technology Process of (2R,3S)-tert-butyl 2-(diphenylmethyleneamino)-3-(4-fluorophenyl)-5-oxo-5-phenylpentanoate

There total 2 articles about (2R,3S)-tert-butyl 2-(diphenylmethyleneamino)-3-(4-fluorophenyl)-5-oxo-5-phenylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 81477-94-3
N-(diphenylmethylene)glycine tert-butyl ester

: 1608-51-1,22966-07-0,102692-46-6
4-fluorochalcone

: 1268449-14-4
(2R,3S)-tert-butyl 2-(diphenylmethyleneamino)-3-(4-fluorophenyl)-5-oxo-5-phenylpentanoate

Guidance literature:: With 2Br^(1-)*C₁₄₅H₈₈F₄₈N₂⁽²⁺⁾; caesium carbonate; In 5,5-dimethyl-1,3-cyclohexadiene; at -15 ℃; for 12h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c0cc04321d