[(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide

Base Information

• Chemical Name: [(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide
• CAS No.: 1010821-36-9
• Molecular Formula: C₂₉H₄₁NO₇Si
• Molecular Weight: 543.733

Synonyms:[(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide

Chemical Property of [(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide

There total 1 articles about [(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

[(2R,3R,4S,5S)-1-azido-2-(3',4'-methylenedioxy)phenyl-3-(O)-benzoyl-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexane (1010821-35-8) → [(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide (1010821-36-9)

Guidance literature:

With 10% Pd/C; hydrogen; at 20 ℃; for 2h; under 760.051 Torr;

DOI:10.1021/np0705460

Reference yield: 96.0%

[(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide (1010821-36-9) → [(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3,6-dihydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide (1010821-37-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1021/np0705460

Reference yield: 95.0%

[(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide (1010821-36-9) + chloromethyl methyl ether (107-30-2) → [(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-methoxymethyleneoxy-4,5-isopropylidene-dioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide (1194061-00-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 10h;

DOI:10.1016/j.bmcl.2009.08.032

upstream raw materials:

[(2R,3R,4S,5S)-1-azido-2-(3',4'-methylenedioxy)phenyl-3-(O)-benzoyl-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexane

Downstream raw materials:

[(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3,6-dihydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide

[(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3,4,5,6-tetrahydroxy]hexyl benzamide

[(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-methoxymethyleneoxy-4,5-isopropylidene-dioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1010821-36-9 [(2R,3R,4S,5S)-2-(3',4'-methylenedioxy)phenyl-3-hydroxy-4,5-isopropylidenedioxy-6-tert-butyldimethylsilyloxy]hexyl benzamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send