4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate

Base Information

• Chemical Name: 4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate
• CAS No.: 1621401-85-1
• Molecular Formula: C₂₅H₂₂O₁₂
• Molecular Weight: 514.442
• Mol file: 1621401-85-1.mol

Synonyms:4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate

Chemical Property of 4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate

There total 1 articles about 4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetic acid 2-acetoxy-4-(3,5-diacetoxy-7-hydroxy-4-oxo-4H-chromen-2-yl)-phenyl ester (143631-95-2) + chloromethyl methyl ether (107-30-2) → 4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate (1621401-85-1)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 4h;

DOI:10.1016/j.bmc.2016.12.034

Reference yield: 95.0%

4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate (1621401-85-1) → 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-(methoxymethoxy)-4H-chromen-4-one

Guidance literature:

With methanol; ammonia; at 0 ℃; for 4h;

DOI:10.1016/j.bmc.2016.12.034

Reference yield:

4-[3,5-diacetoxy-7-(methoxymethoxy)-4-oxo-4H-chromen-2-yl]-1,2-phenylene diacetate (1621401-85-1) → 2-(3-acetoxy-4-hydroxyphenyl)-7-(methoxymethoxy)-4-oxo-4H-chromene-3,5-diyl diacetate (1621401-87-3) + 2-(4-acetoxy-3-hydroxyphenyl)-7-(methoxymethoxy)-4-oxo-4H-chromene-3,5-diyl diacetate (1621401-89-5)

Guidance literature:

With 1H-imidazole; thiophenol; In 1-methyl-pyrrolidin-2-one; at -20 ℃; for 20h; Overall yield = 92%; Overall yield = 8.43 g;

DOI:10.1055/s-0033-1338559

upstream raw materials:

acetic acid 2-acetoxy-4-(3,5-diacetoxy-7-hydroxy-4-oxo-4H-chromen-2-yl)-phenyl ester

chloromethyl methyl ether

Downstream raw materials:

2-(3-acetoxy-4-hydroxyphenyl)-7-(methoxymethoxy)-4-oxo-4H-chromene-3,5-diyl diacetate

2-(4-acetoxy-3-hydroxyphenyl)-7-(methoxymethoxy)-4-oxo-4H-chromene-3,5-diyl diacetate

2-[3,4-diacetoxy-5-(3-methylbut-2-enyl)phenyl]-7-(methoxymethoxy)-4-oxo-4H-chromene-3,5-diyl diacetate

C₂₈H₂₈O₁₁