(Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

Base Information

Chemical Name:(Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide
CAS No.:1367282-60-7
Molecular Formula:C₂₆H₂₁Cl₂F₄N₃O₃
Molecular Weight:570.371
Hs Code.:

Synonyms:(Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

Suppliers and Price of (Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

There total 12 articles about (Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1367283-14-4
4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-oxoethyl)-1-naphthamide

: 50632-53-6
N-isopropylhydroxylamine hydrochloride

: 1367282-60-7
(Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

: 1367282-58-3
(E)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

Guidance literature:: With potassium acetate; In ethanol; water; at 130 ℃; for 0.416667h; Microwave irradiation;

Reference yield:

: 35615-97-5
4-bromo-naphthalene-1-carboxylic acid methyl ester

: 1367282-60-7
(Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

: 1367282-58-3
(E)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

Guidance literature:: Multi-step reaction with 9 steps

1.1: sodium hydrogencarbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / ethanol; water; toluene / 3 h / Reflux

2.1: ozone / methanol; dichloromethane / -78 °C

3.1: hydroxylamine hydrochloride / ethanol; water / 18 h / 45 °C

4.1: N-chloro-succinimide / N,N-dimethyl-formamide / 3.17 h / 20 °C

5.1: potassium hydrogencarbonate / ethyl acetate / 18 h / 20 °C

6.1: lithium hydroxide / 1,4-dioxane; water / 3 h / 20 °C

7.1: triethylamine; HATU / N,N-dimethyl-formamide / 0.25 h / 20 °C

7.2: 2 h / 20 °C

8.1: Dess-Martin periodane / ethyl acetate / 2 h / 20 °C

9.1: potassium acetate / ethanol; water / 0.42 h / 130 °C / Microwave irradiation

With N-chloro-succinimide; hydroxylamine hydrochloride; potassium acetate; sodium hydrogencarbonate; potassium hydrogencarbonate; Dess-Martin periodane; ozone; triethylamine; HATU; lithium hydroxide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; methanol; ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; toluene;

Reference yield:

: 16650-55-8
4-bromonaphthalene-1-carboxylic acid

: 1367282-60-7
(Z)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

: 1367282-58-3
(E)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-(isopropoxyimino)ethyl)-1-naphthamide

Guidance literature:: Multi-step reaction with 10 steps

1.1: sulfuric acid / 18 h / Reflux

2.1: sodium hydrogencarbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / ethanol; water; toluene / 3 h / Reflux

3.1: ozone / methanol; dichloromethane / -78 °C

4.1: hydroxylamine hydrochloride / ethanol; water / 18 h / 45 °C

5.1: N-chloro-succinimide / N,N-dimethyl-formamide / 3.17 h / 20 °C

6.1: potassium hydrogencarbonate / ethyl acetate / 18 h / 20 °C

7.1: lithium hydroxide / 1,4-dioxane; water / 3 h / 20 °C

8.1: triethylamine; HATU / N,N-dimethyl-formamide / 0.25 h / 20 °C

8.2: 2 h / 20 °C

9.1: Dess-Martin periodane / ethyl acetate / 2 h / 20 °C

10.1: potassium acetate / ethanol; water / 0.42 h / 130 °C / Microwave irradiation

With N-chloro-succinimide; sulfuric acid; hydroxylamine hydrochloride; potassium acetate; sodium hydrogencarbonate; potassium hydrogencarbonate; Dess-Martin periodane; ozone; triethylamine; HATU; lithium hydroxide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; methanol; ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; toluene;