Technology Process of (E)-3-(3,4-dimethylphenyl)acrylaldehyde
There total 2 articles about (E)-3-(3,4-dimethylphenyl)acrylaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine; isobutyl chloroformate;
In
tetrahydrofuran;
at 0 ℃;
for 0.5h;
With
sodium tetrahydroborate; water;
at 0 ℃;
for 0.5h;
With
Dess-Martin periodane;
In
dichloromethane;
at 20 ℃;
for 3h;
- Guidance literature:
-
With
dimethyl 2-((6-methylpyridin-3-yl)methylene)malonate; silver(I) acetate; palladium diacetate; N-acetylglycine;
at 90 ℃;
for 24h;
regioselective reaction;
Schlenk technique;
Inert atmosphere;
Sealed tube;
DOI:10.1002/anie.201712235
- Guidance literature:
-
With
(5aR,10bS)-5a,10b-dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran;
at 20 ℃;
for 4h;
stereoselective reaction;
Schlenk technique;
Inert atmosphere;
Sealed tube;
DOI:10.1021/acs.orglett.7b01860
