N^α-tert-butyl-oxycarbonyl-N^ε-benzyloxycarbonyl-L-lysyl-N^G-nitro-L-arginine benzyl ester

Base Information

• Chemical Name: N^α-tert-butyl-oxycarbonyl-N^ε-benzyloxycarbonyl-L-lysyl-N^G-nitro-L-arginine benzyl ester
• CAS No.: 59658-49-0
• Molecular Formula: C₃₂H₄₅N₇O₉
• Molecular Weight: 671.751

Synonyms:N^α-tert-butyl-oxycarbonyl-N^ε-benzyloxycarbonyl-L-lysyl-N^G-nitro-L-arginine benzyl ester

Chemical Property of N^α-tert-butyl-oxycarbonyl-N^ε-benzyloxycarbonyl-L-lysyl-N^G-nitro-L-arginine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-tert-butyl-oxycarbonyl-N^ε-benzyloxycarbonyl-L-lysyl-N^G-nitro-L-arginine benzyl ester

There total 3 articles about N^α-tert-butyl-oxycarbonyl-N^ε-benzyloxycarbonyl-L-lysyl-N^G-nitro-L-arginine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Boc-Lys(Z)-OH (2389-45-9) + Nω-nitro-L-arginine benzyl ester (7672-27-7) → Nα-tert-butyl-oxycarbonyl-Nε-benzyloxycarbonyl-L-lysyl-NG-nitro-L-arginine benzyl ester (59658-49-0)

Guidance literature:

With TOS; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; N-cyclohexyl-cyclohexanamine; In N,N-dimethyl-formamide; at 0 - 4 ℃; for 12h;

DOI:10.1248/cpb.29.2322

Reference yield:

Boc-Lys(Z)-OH (2389-45-9) → Nα-tert-butyl-oxycarbonyl-Nε-benzyloxycarbonyl-L-lysyl-NG-nitro-L-arginine benzyl ester (59658-49-0)

Guidance literature:

Multi-step reaction with 2 steps

1: N-ethylmorpholine / CHCl₃ / 0.17 h / -20 °C

2: N-ethylmorpholine / CHCl₃ / 1.) 0 deg C, 1 h, 2.) RT, overnight

With N-ethylmorpholine;; In chloroform;

Reference yield:

Boc-Lys(Z)-OCOOEt (126583-16-2) + NG-NO2-ArgOBzl*pTs (10342-07-1) → Nα-tert-butyl-oxycarbonyl-Nε-benzyloxycarbonyl-L-lysyl-NG-nitro-L-arginine benzyl ester (59658-49-0)

Guidance literature:

With N-ethylmorpholine;; In chloroform; Yield given; 1.) 0 deg C, 1 h, 2.) RT, overnight;

upstream raw materials:

Boc-Lys(Z)-OH

N^ω-nitro-L-arginine benzyl ester

Boc-Lys(Z)-OCOOEt

N^G-NO₂-ArgOBzl*pTs

Downstream raw materials:

Boc-Thr-Leu-Thr-Ala-Val-Lys(Z)-Arg(NO₂)-OBzl

Boc-Leu-Thr-Ala-Val-Lys(Z)-Arg(NO₂)-OBzl

Boc-Thr-Ala-Val-Lys(Z)-Arg(NO₂)-OBzl

Boc-Ala-Val-Lys(Z)-Arg(NO₂)-OBzl

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 59658-49-0 N^α-tert-butyl-oxycarbonyl-N^ε-benzyloxycarbonyl-L-lysyl-N^G-nitro-L-arginine benzyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send