(R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide

Base Information

• Chemical Name: (R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide
• CAS No.: 1191080-52-0
• Molecular Formula: C₁₉H₃₁NOS
• Molecular Weight: 321.527
• Mol file: 1191080-52-0.mol

Synonyms:(R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide

Chemical Property of (R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide

There total 1 articles about (R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-Di-tert-butylbenzaldehyde (17610-00-3) + (R)-2-methylpropane-2-sulfinamide (196929-78-9) → (R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide (1191080-52-0)

Guidance literature:

With titanium(IV) isopropylate; In tetrahydrofuran; at 60 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2015.12.002

Reference yield: 52.0%

(R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide (1191080-52-0) + (lithiomethyl)diphenylphosphane (62263-69-8) → C32H44NOPS

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; boron trifluoride diethyl etherate; In tetrahydrofuran; at 20 ℃; diastereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2015.12.002

Reference yield:

(R)-N-(3,5-di-tert-butylbenzylidene)-2-methylpropane-2-sulfinamide (1191080-52-0) → (R,R)-N,N'-((1S,2S)-1,2-bis(3,5-di-tert-butylphenyl)ethane-1,2-diyl)bis(2-methylpropane-2-sulfinamide) (1191080-56-4)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at -78 ℃; Inert atmosphere;

DOI:10.1021/ol901674k

upstream raw materials:

3,5-Di-tert-butylbenzaldehyde

(R)-2-methylpropane-2-sulfinamide

Downstream raw materials:

(R,R)-N,N'-((1S,2S)-1,2-bis(3,5-di-tert-butylphenyl)ethane-1,2-diyl)bis(2-methylpropane-2-sulfinamide)