1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene

Base Information

• Chemical Name: 1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene
• CAS No.: 443096-40-0
• Molecular Formula: C₃₂H₆₄GeSi₆
• Molecular Weight: 689.963
• Mol file: 443096-40-0.mol

Synonyms:1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene

Chemical Property of 1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene

There total 7 articles about 1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-chloro-1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germacyclohexa-2,4-diene (443096-46-6) → 1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene (443096-40-0)

Guidance literature:

With lithium diisopropylamide; In tetrahydrofuran; n-heptane; ethylbenzene; under Ar; soln. of lithium diisopropylamide in heptane/THF/ethylbenzene added to the germacyclohexadiene in THF at room temp., stirred for 1 h; solvents removed under vac., hexane added to residue, mixt. was left for10 h, ppt. removed, filtrate evapd.; elem. anal.;

DOI:10.1021/ja0262941

Reference yield:

5-iodopenta-1,4-dienyl(dimethoxy)(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)germane → 1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene (443096-40-0)

Guidance literature:

Multi-step reaction with 3 steps

1: tert-butyllithium; HCl; SiO₂ / diethyl ether; pentane

2: diethyl ether

3: lithium diisopropylamide / tetrahydrofuran; n-heptane; ethylbenzene

With tert-butyllithium; HCl; SiO₂; lithium diisopropylamide; In tetrahydrofuran; diethyl ether; n-heptane; ethylbenzene; pentane;

DOI:10.1021/ja0262941

Reference yield:

trimethoxy(2,4,6-tris(bis(trimethylsilyl)methyl)phenyl)germane (443096-41-1) → 1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germabenzene (443096-40-0)

Guidance literature:

Multi-step reaction with 5 steps

1: NH₄Cl / diethyl ether; hexane

2: Na₂S₂O₃ / dichloromethane

3: tert-butyllithium; HCl; SiO₂ / diethyl ether; pentane

4: diethyl ether

5: lithium diisopropylamide / tetrahydrofuran; n-heptane; ethylbenzene

With NH₄Cl; Na₂S₂O₃; tert-butyllithium; HCl; SiO₂; lithium diisopropylamide; In tetrahydrofuran; diethyl ether; hexane; n-heptane; dichloromethane; ethylbenzene; pentane;

DOI:10.1021/ja0262941

upstream raw materials:

1-chloro-1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germacyclohexa-2,4-diene

trimethoxy(2,4,6-tris(bis(trimethylsilyl)methyl)phenyl)germane

1-hydroxy-1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germacyclohexa-2,4-diene

1,1-dibutyl-1-stannacyclohexa-2,5-diene

Downstream raw materials:

1-hydroxy-1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germacyclohexa-2,4-diene

1-hydroxy-1-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1-germacyclohexa-2,5-diene

3-mesityl-7a-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-3a,7a-dihydro-1-oxa-2-aza-7a-germaindene

2,3-dimethyl-4a-(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)-1,4,4a,8a-tetrahydro-4a-germanaphthalene