(2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone

Base Information

Chemical Name:(2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone
CAS No.:218933-96-1
Molecular Formula:C₁₆H₂₆N₂O₃S
Molecular Weight:326.46
Hs Code.:

Synonyms:(2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone

Suppliers and Price of (2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone

There total 1 articles about (2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59983-39-0,187035-29-6
(S)-1-amino-2-(methoxymethyl)pyrrolidine

: 74963-80-7
(E)-(but-1-en-1-ylsulfonyl)benzene

: 218933-96-1
(2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone

: (2S,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone

Guidance literature:: With ytterbium(III) triflate; In tetrahydrofuran; for 480h; Yield given; Yields of byproduct given; Ambient temperature;
DOI:10.1002/(sici)1521-3773(19990115)38:1/2<195::aid-anie195>3.0.co;2-6

Reference yield:

: 218933-96-1
(2R,2'S)-2-[(2'-(methoxymethyl)pyrrolidin-1'-yl)amino]butyl phenyl sulfone

: (R)-2-(tert-butoxycarbonylamino)butyl phenyl sulfone

Guidance literature:: Multi-step reaction with 2 steps

1: BH₃*THF / tetrahydrofuran / 5 h / Heating

2: 1.88 g / Et₃N / methanol / 48 h / 20 °C

With borane-THF; triethylamine; In tetrahydrofuran; methanol; 1: Reduction / 2: Acylation;
DOI:10.1002/(sici)1099-0690(200003)2000:6<879::aid-ejoc879>3.0.co;2-e