3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester

Base Information

• Chemical Name: 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester
• CAS No.: 25206-13-7
• Molecular Formula: C₂₆H₂₂N₂O₂
• Molecular Weight: 394.473

Synonyms:3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester

Chemical Property of 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester

Chemical Property:

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Technology Process of 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester

There total 2 articles about 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N-Methoxy-N-methyl[2-(1-triphenylmethylimidazol-4-yl)cyclopropyl]carboxamide → 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester (25206-13-7)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; water;

Reference yield:

→ 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester (25206-13-7)

Guidance literature:

2-Butyl 2-(1-Triphenylmethyl-4-imidazolyl)-cyclopropanecarboxylate, in wss.-ethanol. KOH;

DOI:10.1021/jm00295a009

Reference yield:

(R)-1-phenyl-ethyl-amine (3886-69-9) + 3-[1-(triphenylmethyl)-1H-imidazol-4-yl]-cyclopropanecarboxylic acid ester (25206-13-7) + isobutyl chloroformate (543-27-1) → N-((1S)-1-Phenylethyl)[(2S,1R)-2-(1-triphenylmethylimidazol-4-yl)cyclopropyl]carboxamide

Guidance literature:

With triethylamine; In methanol; dichloromethane; water;

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