3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone

Base Information

• Chemical Name: 3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone
• CAS No.: 1201799-40-7
• Molecular Formula: C₁₇H₁₄ClN₃O₃
• Molecular Weight: 343.769
• Mol file: 1201799-40-7.mol

Synonyms:3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone

Chemical Property of 3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone

There total 3 articles about 3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

5-chloro-3-diazo-1,3-dihydro-2H-indol-2-one (100487-78-3) + 3,4-dimethoxy-benzaldehyde (120-14-9) → 3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone (1201799-40-7)

Guidance literature:

With acetic acid; In ethanol; for 4h; Reflux;

DOI:10.1371/journal.pone.0181241

Reference yield:

5-chloroindole 2,3-dione (17630-76-1) → 3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone (1201799-40-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / 0.42 h / Reflux

2: methanol / 3 h / Reflux

With hydrazine hydrate; In methanol;

Reference yield:

→ 3,4-dimethoxybenzaldehyde-N-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone (1201799-40-7)

Guidance literature:

With acetic acid; In ethanol; for 0.166667h; under 760.051 Torr; Microwave irradiation; Sealed tube; Heating;

upstream raw materials:

5-chloro-3-diazo-1,3-dihydro-2H-indol-2-one

3,4-dimethoxy-benzaldehyde

5-chloroindole 2,3-dione