ETHYL 2-HYDROXY-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBOXYLATE

Base Information

• Chemical Name: ETHYL 2-HYDROXY-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBOXYLATE
• CAS No.: 52578-37-7
• Molecular Formula: C₁₁H₁₀N₂O₄
• Molecular Weight: 234.211
• Mol file: 52578-37-7.mol

Synonyms:ethyl 2-hydroxy-4-oxo-4H-pyrido<1,2-a>pyrimidine-3-carboxylate

Chemical Property of ETHYL 2-HYDROXY-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBOXYLATE

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

ETHYL-2-HYDROXY-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ETHYL 2-HYDROXY-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBOXYLATE

There total 4 articles about ETHYL 2-HYDROXY-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-aminopyridine (504-29-0) + methanetricarboxylic acid triethyl ester (6279-86-3) → ethyl 2-hydroxy-4-oxo-4H-pyrido<1,2-a>pyrimidine-3-carboxylate (52578-37-7)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; at 140 ℃; for 4h; Inert atmosphere;

Reference yield: 76.0%

2-aminopyridine (504-29-0) + methanetricarboxylic acid triethyl ester (6279-86-3) → 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid pyrid-2-ylamide (224313-75-1) + ethyl 2-hydroxy-4-oxo-4H-pyrido<1,2-a>pyrimidine-3-carboxylate (52578-37-7)

Guidance literature:

In xylene; Heating;

DOI:10.1007/s10593-007-0119-5

Reference yield:

2-aminopyridine (504-29-0) + diethyl 2-ethoxymethylenemalonate (87-13-8) → ethyl 2-hydroxy-4-oxo-4H-pyrido<1,2-a>pyrimidine-3-carboxylate (52578-37-7)

Guidance literature:

at 140 ℃; for 3h;

upstream raw materials:

2-aminopyridine

methanetricarboxylic acid triethyl ester

diethyl 2-ethoxymethylenemalonate

Downstream raw materials:

Ethyl 4-oxo-2-(phenylamino)-4H-pyrido[1,2-a]pyrimidine-3-carboxylate

3-(Hydroxymethyl)-2-(phenylamino)-4H-pyrido[1,2-a]pyrimidin-4-one

(4-Oxo-2-(phenylamino)-4H-pyrido[1,2-a]pyrimidin-3-yl)methyl benzoate

C₁₅H₁₀FN₃O₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 52578-37-7 ETHYL 2-HYDROXY-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDINE-3-CARBOXYLATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send