Technology Process of 3-tertbutyl-5-(cyclohexylmethyl)-6-phenyl-8-nitrophenanthridinium chloride
There total 7 articles about 3-tertbutyl-5-(cyclohexylmethyl)-6-phenyl-8-nitrophenanthridinium chloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C30H33FN2O2;
In
acetonitrile;
at 110 ℃;
for 1.5h;
Inert atmosphere;
Sealed tube;
Microwave irradiation;
With
hydrogenchloride;
In
diethyl ether;
DOI:10.1002/chem.201304241
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: nitrosonium tetrafluoroborate / dichloromethane / 13.5 h / 0 - 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere; Reflux
2.1: n-butyllithium / tetrahydrofuran / 2.33 h / -77 °C
2.2: 14.17 h / -77 - 20 °C
2.3: 55 h
3.1: [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; N-ethyl-N,N-diisopropylamine / ethanol / 4 h / Inert atmosphere; Reflux
4.1: titanium tetrachloride / toluene / 20.08 h / 0 - 20 °C / Inert atmosphere
5.1: acetonitrile / 1.5 h / 110 °C / Inert atmosphere; Sealed tube; Microwave irradiation
With
n-butyllithium; [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; titanium tetrachloride; nitrosonium tetrafluoroborate; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; ethanol; dichloromethane; toluene; acetonitrile;
1.1: |Balz-Schiemann Reaction / 3.1: |Suzuki-Miyaura Coupling;
DOI:10.1002/chem.201304241
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / tetrahydrofuran / 2.33 h / -77 °C
1.2: 14.17 h / -77 - 20 °C
1.3: 55 h
2.1: [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; N-ethyl-N,N-diisopropylamine / ethanol / 4 h / Inert atmosphere; Reflux
3.1: titanium tetrachloride / toluene / 20.08 h / 0 - 20 °C / Inert atmosphere
4.1: acetonitrile / 1.5 h / 110 °C / Inert atmosphere; Sealed tube; Microwave irradiation
With
n-butyllithium; [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; titanium tetrachloride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; ethanol; toluene; acetonitrile;
2.1: |Suzuki-Miyaura Coupling;
DOI:10.1002/chem.201304241
