Technology Process of 4,4,5,5-tetramethyl-2-[1-methyl-4-(2-methyl-[1,3]dioxolan-2-yl)-1-phenylsulfanyl-butyl]-[1,3,2]dioxaborolane
There total 4 articles about 4,4,5,5-tetramethyl-2-[1-methyl-4-(2-methyl-[1,3]dioxolan-2-yl)-1-phenylsulfanyl-butyl]-[1,3,2]dioxaborolane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
n-butyllithium; diisopropylamine;
In
tetrahydrofuran;
under Ar or N2, first BuLi was added to diisopropylamine in THF with stirring at 0°C, then addn. of B compd., stirring for 12 h at 0°C, addn. of alkyl halide, mixt. kept for 2-4 h at room temp.; addn. of aq. 10 % phosphoric acid, extd. with ether, distd. elem.anal.,yield only 48 % after 3 h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diethyl ether
2: (i) LDA, THF, (ii) /BRN= 969135/
3: (i) LDA, TMEDA, THF, (ii) /BRN= 104617/
In
diethyl ether;
DOI:10.1021/ja00472a066
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diethyl ether
2: (i) LDA, THF, (ii) /BRN= 969135/
3: (i) LDA, TMEDA, THF, (ii) /BRN= 104617/
In
diethyl ether;
DOI:10.1021/ja00472a066
