1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole

Base Information

Chemical Name:1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole
CAS No.:475570-49-1
Molecular Formula:C₁₉H₂₁N₃O₁₀S
Molecular Weight:483.456
Hs Code.:

Synonyms:1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole

Suppliers and Price of 1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole

Chemical Property:

Purity/Quality:: 99% ,98%,Electron Grade , ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole

There total 5 articles about 1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 108-24-7
acetic anhydride

: 639079-78-0
1-β-D-[5-O-toluenesulfonyl-2-O-acetyl-arabinofuranosyl]-2-nitroimidazole

: 475570-49-1,494775-35-8
1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole

Guidance literature:: With pyridine; at 22 ℃; for 3h;
DOI:10.1248/cpb.51.399

Reference yield:

: 108-24-7
acetic anhydride

: 98-59-9
p-toluenesulfonyl chloride

: 639079-77-9
1-β-D-[2-O-acetyl-arabinofuranosyl]-2-nitroimidazole

: 475570-49-1,494775-35-8
1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole

Guidance literature:: p-toluenesulfonyl chloride; 1-β-D-[2-O-acetyl-arabinofuranosyl]-2-nitroimidazole; In pyridine; at 0 ℃; for 18h;

acetic anhydride; In pyridine; for 3h;

Reference yield:

: 639079-75-7
1-β-D-[3,5-O,O-(1,1,3,3-tetraisopropyldisiloxanyl)-2-O-acetylarabinofuranosyl]-2-nitroimidazole

: 475570-49-1,494775-35-8
1-β-D-[5-O-toluenesulfonyl-2,3-di-O-acetylarabinofuranosyl]-2-nitroimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / potassium fluoride; benzoic acid / acetonitrile / 75 °C

2: 52 percent / pyridine; DMAP / 78 h / -5 - 22 °C

3: 88 percent / pyridine / 3 h / 22 °C

With pyridine; dmap; potassium fluoride; benzoic acid; In acetonitrile;
DOI:10.1248/cpb.51.399