benzofuro<2,3-c>pyridine

Base Information

• Chemical Name: benzofuro<2,3-c>pyridine
• CAS No.: 54499-49-9
• Molecular Formula: C₁₁H₇NO
• Molecular Weight: 169.183
• Mol file: 54499-49-9.mol

Synonyms:benzofuro<2,3-c>pyridine

Chemical Property of benzofuro<2,3-c>pyridine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Benzofuro[3,2-b]pyridine 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzofuro<2,3-c>pyridine

There total 1 articles about benzofuro<2,3-c>pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

3-pyridyl 2-(allyloxy)benzoate (1245937-14-7) → C6H3N3O7*C11H7NO (84558-13-4) + benzofuro<2,3-c>pyridine (54499-49-9)

Guidance literature:

3-pyridyl 2-(allyloxy)benzoate; at 650 ℃; for 1h; under 0.001 Torr; Flash vacuum pyrolysis;

With 2,4,6-Trinitrophenol; In diethyl ether; ethanol; acetone;

DOI:10.1039/c002480e

Reference yield: 81.0%

benzofuro<2,3-c>pyridine (54499-49-9) → 2-(2-hydroxyphenyl)pyridin-3-ol (144190-35-2)

Guidance literature:

With potassium hydroxide; at 275 ℃; for 5h;

Reference yield:

benzofuro<2,3-c>pyridine (54499-49-9) → C17H10BrNO (1384187-13-6)

Guidance literature:

Multi-step reaction with 3 steps

1: bromine / nitrobenzene / 12 h / 140 °C

2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 16 h / 80 °C / Inert atmosphere

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; 1,2-dimethoxyethane / 8 h / Reflux; Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; bromine; potassium acetate; sodium carbonate; In 1,2-dimethoxyethane; water; dimethyl sulfoxide; nitrobenzene;

upstream raw materials:

3-pyridyl 2-(allyloxy)benzoate

Downstream raw materials:

2-(2-hydroxyphenyl)pyridin-3-ol

C₁₇H₁₀BrNO

C₂₃H₂₂BNO₃