Dpofa

Base Information

Chemical Name:Dpofa
CAS No.:81997-33-3
Molecular Formula:C18H18Cl2O4
Molecular Weight:369.2391
Hs Code.:
UNII:SC0Y88002K
DSSTox Substance ID:DTXSID10231500
Nikkaji Number:J138.353A
Wikidata:Q27289137

Synonyms:((5,6-dichloro-2,3,9,9a-tetrahydro-3-oxo-9a-propyl-1H-fluoren-7-yl)oxy)acetic acid;((5,6-dichloro-9a-n-propyl-2,3,9,9a-tetrahydro-3-oxo-1H-fluren-7-yl)oxy)acetic acid;B-3(+);DPOFA;L 644711;L 644711, (S)-isomer;L-644,711;L-644711

Suppliers and Price of Dpofa

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Dpofa

Chemical Property:

Vapor Pressure:1.43E-12mmHg at 25°C
Boiling Point:541.8°C at 760 mmHg
Flash Point:281.5°C
Density:1.41g/cm³
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:368.0582144
Heavy Atom Count:24
Complexity:561

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC12CCC(=O)C=C1C3=C(C(=C(C=C3C2)OCC(=O)O)Cl)Cl
Isomeric SMILES:CCC[C@]12CCC(=O)C=C1C3=C(C(=C(C=C3C2)OCC(=O)O)Cl)Cl

Technology Process of Dpofa

There total 24 articles about Dpofa which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55507-82-9
(1-Oxo-2-n-propyl-6,7-dichloro-5-indanyloxy)-acetic Acid

: 81997-30-0,81997-33-3,101469-39-0,103433-13-2
(3,4-Dichloro-6-oxo-8a-propyl-7,8,8a,9-tetrahydro-6H-fluoren-2-yloxy)-acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / conc. H₂SO₄ / 2 h / Heating

2: 66 percent / 1,5-diazabicyclo<4.3.0>non-5-ene (DBN) / tetrahydrofuran / 16 h / Ambient temperature

3: 25 percent / pyrrolidine, AcOH / toluene / 1.5 h / 85 °C

4: 87 percent / 5percent aq. HCl / acetic acid / 1 h / 100 °C

With pyrrolidine; hydrogenchloride; sulfuric acid; DBN; acetic acid; In tetrahydrofuran; acetic acid; toluene;
DOI:10.1021/jm00155a038

Reference yield:

: 55507-82-9
(1-Oxo-2-n-propyl-6,7-dichloro-5-indanyloxy)-acetic Acid

: 81997-30-0,81997-33-3,101469-39-0,103433-13-2
(3,4-Dichloro-6-oxo-8a-propyl-7,8,8a,9-tetrahydro-6H-fluoren-2-yloxy)-acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / conc. H₂SO₄ / 2 h / Heating

2: 66 percent / 1,5-diazabicyclo<4.3.0>non-5-ene (DBN) / tetrahydrofuran / 16 h / Ambient temperature

3: 25 percent / pyrrolidine, AcOH / toluene / 1.5 h / 85 °C

4: 87 percent / 5percent aq. HCl / acetic acid / 1 h / 100 °C

With pyrrolidine; hydrogenchloride; sulfuric acid; DBN; acetic acid; In tetrahydrofuran; acetic acid; toluene;
DOI:10.1021/jm00155a038

Reference yield:

: 83429-37-2
(6,7-Dichloro-1-oxo-2-propyl-indan-5-yloxy)-acetic acid methyl ester

: 81997-30-0,81997-33-3,101469-39-0,103433-13-2
(3,4-Dichloro-6-oxo-8a-propyl-7,8,8a,9-tetrahydro-6H-fluoren-2-yloxy)-acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 66 percent / 1,5-diazabicyclo<4.3.0>non-5-ene (DBN) / tetrahydrofuran / 16 h / Ambient temperature

2: 25 percent / pyrrolidine, AcOH / toluene / 1.5 h / 85 °C

3: 87 percent / 5percent aq. HCl / acetic acid / 1 h / 100 °C

With pyrrolidine; hydrogenchloride; DBN; acetic acid; In tetrahydrofuran; acetic acid; toluene;
DOI:10.1021/jm00155a038