6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether

Base Information

Chemical Name:6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether
CAS No.:1312551-39-5
Molecular Formula:C₃₂H₄₀O₆Si
Molecular Weight:548.751
Hs Code.:

Synonyms:6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether

Suppliers and Price of 6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether

There total 1 articles about 6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 2746-25-0
p-Methoxybenzyl bromide

: 103763-14-0
(3aR,5S,6S,6aR)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-ol

: 1312551-39-5
6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether

Guidance literature:: (3aR,5S,6S,6aR)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-ol; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

p-Methoxybenzyl bromide; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1039/c1ob00019e

Reference yield: 89.0%

: 1312551-39-5
6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether

: 1312551-41-9
6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methanol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1039/c1ob00019e

Reference yield:

: 1312551-39-5
6-(4-methoxybenzyloxy)-2,2-dimethyl-(3aR,5S,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxol-5-yl-methyl tert-butyldiphenylsilyl ether

: 1312551-47-5
(3aR,5S,6S,6aR)-6-(4-methoxybenzyloxy)-tetrahydro-2,2-dimethyl-5-vinylfuro[3,2-d][1,3]dioxole

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide / 10 - 20 °C / Inert atmosphere

3.1: potassium tert-butylate / tetrahydrofuran / 6 h / 0 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

With potassium tert-butylate; tetrabutyl ammonium fluoride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1039/c1ob00019e