(R)-N-(4-methyl-4-(methoxycarbonyloxy)pent-2-ynyl)-N-(1-pentyn-3-yl)tosylamide

Base Information

• Chemical Name: (R)-N-(4-methyl-4-(methoxycarbonyloxy)pent-2-ynyl)-N-(1-pentyn-3-yl)tosylamide
• CAS No.: 1092371-86-2
• Molecular Formula: C₂₀H₂₅NO₅S
• Molecular Weight: 391.488

Synonyms:(R)-N-(4-methyl-4-(methoxycarbonyloxy)pent-2-ynyl)-N-(1-pentyn-3-yl)tosylamide

Chemical Property of (R)-N-(4-methyl-4-(methoxycarbonyloxy)pent-2-ynyl)-N-(1-pentyn-3-yl)tosylamide

Chemical Property:

Purity/Quality:

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Technology Process of (R)-N-(4-methyl-4-(methoxycarbonyloxy)pent-2-ynyl)-N-(1-pentyn-3-yl)tosylamide

There total 1 articles about (R)-N-(4-methyl-4-(methoxycarbonyloxy)pent-2-ynyl)-N-(1-pentyn-3-yl)tosylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H33NO5SSi → (R)-N-(4-methyl-4-(methoxycarbonyloxy)pent-2-ynyl)-N-(1-pentyn-3-yl)tosylamide (1092371-86-2)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1002/anie.200803424

Reference yield: 73.0%

(R)-N-(4-methyl-4-(methoxycarbonyloxy)pent-2-ynyl)-N-(1-pentyn-3-yl)tosylamide (1092371-86-2) + 2,4-dimethylpenta-2,3-dienoic acid (102104-08-5) → C25H31NO4S (1092371-87-3)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In nitromethane; at 60 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.200803424

Downstream raw materials:

C₂₅H₃₁NO₄S

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