Technology Process of C25H36ClIN2O5
There total 12 articles about C25H36ClIN2O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(1S,2S,3S,5R)-(+)-isopinocampheylamine;
With
trimethylaluminum;
In
hexanes; dichloromethane;
for 0.325h;
C15H17ClINO5;
In
hexanes; dichloromethane;
at 20 ℃;
With
sodium sulfate;
In
dichloromethane; water;
at 20 ℃;
for 15h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: pyridine / dmap / dichloromethane / 1 h / 0 - 20 °C
2.1: sodium iodide / acetone / 6 h / 20 °C
3.1: silver nitrate / acetonitrile / 6 h / 20 °C
4.1: sodium acetate / dimethyl sulfoxide / 0.5 h / 20 °C
5.1: toluene / 14 h / Heating / reflux
6.1: hydrogenchloride / tetrahydrofuran; water / 2 h / 20 °C
7.1: trimethylaluminum / hexanes; dichloromethane / 0.33 h
7.2: 20 °C
7.3: 15 h / 20 °C
With
pyridine; hydrogenchloride; trimethylaluminum; sodium acetate; silver nitrate; sodium iodide;
dmap;
In
tetrahydrofuran; hexanes; dichloromethane; water; dimethyl sulfoxide; acetone; toluene; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 40 °C
2.1: hydroxylamine hydrochloride / tetrahydrofuran; methanol; water / 0.08 h / 20 °C
3.1: hydrogenchloride; methyl orange; sodium cyanoborohydride / tetrahydrofuran; methanol; water / 3 h / pH 2
4.1: toluene / 14 h / Heating / reflux
5.1: hydrogenchloride / tetrahydrofuran; water / 2 h / 20 °C
6.1: trimethylaluminum / hexanes; dichloromethane / 0.33 h
6.2: 20 °C
6.3: 15 h / 20 °C
With
hydrogenchloride; hydroxylamine hydrochloride; methyl orange; trimethylaluminum; sodium cyanoborohydride; potassium carbonate;
In
tetrahydrofuran; methanol; hexanes; dichloromethane; water; N,N-dimethyl-formamide; toluene;