N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

Base Information

Chemical Name:N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide
CAS No.:618892-18-5
Molecular Formula:C₁₈H₂₂N₂O₅S
Molecular Weight:378.449
Hs Code.:

Synonyms:N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

Suppliers and Price of N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

There total 7 articles about N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 618892-17-4
N-(tert-butoxy)-2(R)-[[(4-methoxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

: 618892-18-5
N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

Guidance literature:: With aluminium trichloride; ethanethiol; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1002/jlcr.675

Reference yield:

: (R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-3-methyl-butyric acid

: 618892-18-5
N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

Guidance literature:: Multi-step reaction with 2 steps

1: EDCI; HOBt; NMM / CH₂Cl₂

2: AlCl₃; EtSH / CH₂Cl₂

With 4-methyl-morpholine; aluminium trichloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; ethanethiol; In dichloromethane;

Reference yield:

: 202751-37-9
methyl 2(R)-[[(4-methoxyphenyl)sulfonyl]benzylamino]-3-methylbutanoate

: 618892-18-5
N-hydroxy-2(R)-[[(4-hydroxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide

Guidance literature:: Multi-step reaction with 3 steps

1: HCl; TFA / Heating

2: EDCI; HOBt; NMM / CH₂Cl₂

3: AlCl₃; EtSH / CH₂Cl₂

With 4-methyl-morpholine; hydrogenchloride; aluminium trichloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; ethanethiol; In dichloromethane;