9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene

Base Information

• Chemical Name: 9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene
• CAS No.: 676363-55-6
• Molecular Formula: C₃₅H₃₂O
• Molecular Weight: 468.638
• Mol file: 676363-55-6.mol

Synonyms:9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene

Chemical Property of 9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene

There total 1 articles about 9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) + 10-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-9-phenylanthracene (676363-26-1) → 9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene (676363-55-6) + C35H32O

Guidance literature:

With isopentyl nitrite; In 1,2-dimethoxyethane; benzene; Heating;

DOI:10.1021/jo035517i

Reference yield: 83.0%

9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene (676363-55-6) → 9-ethynyl-2,3,6,7-tetramethyl-10-phenyltriptycene

Guidance literature:

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; In benzene; at 68 ℃; for 7h;

DOI:10.1021/jo035517i

Reference yield:

9-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-10-phenyltriptycene (676363-55-6) → 1,4-bis{2-[9-(2,3,6,7-tetramethyl-10-phenyltriptycyl)]ethynyl}benzene

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / Bu₄NI; KOH / benzene / 7 h / 68 °C

2: 32 percent / piperidine / Pd(PPh₃)2Cl₂ / 48 h / 90 °C

With piperidine; potassium hydroxide; tetra-(n-butyl)ammonium iodide; bis-triphenylphosphine-palladium(II) chloride; In benzene; 2: Sonogashira coupling;

DOI:10.1021/jo035517i

upstream raw materials:

anthranilic acid

10-(3-hydroxy-3-methyl-1-butynyl)-2,3,6,7-tetramethyl-9-phenylanthracene