(2S,2''S)-1-[N-(1-(1-dimethylethyl)-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

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Chemical Name:(2S,2''S)-1-[N-(1-(1-dimethylethyl)-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine
CAS No.:107300-28-7
Molecular Formula:C₁₉H₃₂N₂O
Molecular Weight:304.476
Hs Code.:

Synonyms:(2S,2''S)-1-[N-(1-(1-dimethylethyl)-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,2''S)-1-[N-(1-(1-dimethylethyl)-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

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Technology Process of (2S,2''S)-1-[N-(1-(1-dimethylethyl)-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

There total 1 articles about (2S,2''S)-1-[N-(1-(1-dimethylethyl)-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 594-19-4
tert.-butyl lithium

: 89999-42-8
(S)-2-methoxymethyl-1-(3-phenylpropylidenamino)pyrrolidine

: 107300-28-7
(2S,2''S)-1-[N-(1-(1-dimethylethyl)-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

Guidance literature:: tert.-butyl lithium; With cerium(III) chloride heptahydrate; In tetrahydrofuran; pentane; at -78 ℃; for 1h; Inert atmosphere;

(S)-2-methoxymethyl-1-(3-phenylpropylidenamino)pyrrolidine; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetasy.2010.04.042