O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate

Base Information

• Chemical Name: O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate
• CAS No.: 1347739-93-8
• Molecular Formula: C₂₉H₃₈N₃O₇P
• Molecular Weight: 571.61
• Mol file: 1347739-93-8.mol

Synonyms:O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate

Chemical Property of O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate

There total 8 articles about O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

C16H28NO3P (1347740-14-0) + 2-(4',6'-dimethoxypyrimidine-2'-yl)oxy-benzoic acid (110284-78-1) → O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate (1347739-93-8)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 25 ℃;

DOI:10.1080/10426507.2011.558363

Reference yield:

C24H34NO3P (1347740-01-5) → O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate (1347739-93-8)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran / 2 h / 0 °C

2: ammonium hydroxide / water / 0.5 h / 20 °C

3: dmap; dicyclohexyl-carbodiimide / dichloromethane / 0 - 25 °C

With dmap; ammonium hydroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water;

DOI:10.1080/10426507.2011.558363

Reference yield:

C7H8O3S*C16H28NO3P → O,O-di-n-butyl [2-(4,6-dimethoxypyrimidin-2-yloxy)phenoxyamino](p-tolyl)methylphosphonate (1347739-93-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium hydroxide / water / 0.5 h / 20 °C

2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 0 - 25 °C

With dmap; ammonium hydroxide; dicyclohexyl-carbodiimide; In dichloromethane; water;

DOI:10.1080/10426507.2011.558363

upstream raw materials:

C₂₄H₃₄NO₃P

C₁₆H₂₈NO₃P

2-(4',6'-dimethoxypyrimidine-2'-yl)oxy-benzoic acid

4-methyl-benzaldehyde