trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline

Base Information

• Chemical Name: trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline
• CAS No.: 1253376-06-5
• Molecular Formula: C₃₄H₃₉NO₇
• Molecular Weight: 573.686

Synonyms:trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline

Chemical Property of trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline

There total 1 articles about trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline allyl ester → trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline (1253376-06-5)

Guidance literature:

With 4-methyl-morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol102112z

Reference yield:

trans-N-tert-butyloxycarbonyl-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline (1253376-06-5) + trans-4-hydroxy-4-[2,3,5-tribenzyl-β-L-arabinofuranosyl]-L-proline allyl ester (1253376-13-4) → C70H80N2O15 (1253375-59-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol102112z

Downstream raw materials:

C₇₀H₈₀N₂O₁₅

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