N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide

Base Information

• Chemical Name: N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide
• CAS No.: 78089-69-7
• Molecular Formula: C₁₄H₁₃Cl₃NOP
• Molecular Weight: 348.596
• Mol file: 78089-69-7.mol

Synonyms:N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide

Chemical Property of N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide

There total 4 articles about N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methylphosphinyl chloride (78089-65-3) + m,p-dichloroaniline (95-76-1) → N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide (78089-69-7)

Guidance literature:

In diethyl ether;

DOI:10.1021/jo00330a021

Reference yield:

ortho-methylphenyl iodide (615-37-2) → N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide (78089-69-7)

Guidance literature:

Multi-step reaction with 4 steps

1: NiCl₂ / 2.5 h / 160 - 170 °C

2: PCl₅ / benzene / 1 h / Heating

3: Cl₂ / CCl₄ / 1.5 h / Heating; Irradiation

4: 99 percent / diethyl ether

With phosphorus pentachloride; chlorine; nickel dichloride; In tetrachloromethane; diethyl ether; benzene;

DOI:10.1021/jo00330a021

Reference yield:

ethyl methyl-o-tolylphosphinate (61820-30-2) → N-(3,4-Dichlorophenyl)-P-(α-chloro-2-tolyl)-P-methylphosphinamide (78089-69-7)

Guidance literature:

Multi-step reaction with 3 steps

1: PCl₅ / benzene / 1 h / Heating

2: Cl₂ / CCl₄ / 1.5 h / Heating; Irradiation

3: 99 percent / diethyl ether

With phosphorus pentachloride; chlorine; In tetrachloromethane; diethyl ether; benzene;

DOI:10.1021/jo00330a021

upstream raw materials:

methylphosphinyl chloride

m,p-dichloroaniline

ortho-methylphenyl iodide

ethyl methyl-o-tolylphosphinate

Downstream raw materials:

1-Methyl-2-(3,4-dichlorophenyl)-2,3-dihydro-1H-2,1-benzazaphosphole 1-Oxide