tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate

Base Information

Chemical Name:tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate
CAS No.:875340-78-6
Molecular Formula:C₂₁H₂₁FN₄O₆S
Molecular Weight:476.485
Hs Code.:

Synonyms:tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate

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Chemical Property of tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate

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Technology Process of tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate

There total 1 articles about tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 875339-24-5
7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carbonyl chloride monohydrochloride

: 79513-35-2,117083-06-4
N-(tert-butyloxycarbonyl)-1,2-ethanediamine hydrochloride

: 875340-78-6
tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 4h;

Reference yield: 100.0%

: 875340-78-6
tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate

: 875340-79-7
tert-butyl 2-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate

Guidance literature:: tert-butyl 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine-2-carboxamido)ethylcarbamate; With sodium tetrahydroborate; nickel dichloride; In tetrahydrofuran; methanol; at 0 ℃; for 0.25h;

With hydrogenchloride; In tetrahydrofuran; methanol; water;