1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol

Base Information

• Chemical Name: 1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol
• CAS No.: 942914-42-3
• Molecular Formula: C₆₂H₁₀₉N₃O₁₉P₂S
• Molecular Weight: 1294.57
• Mol file: 942914-42-3.mol

Synonyms:1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol

Chemical Property of 1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol

There total 1 articles about 1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

N,N-diisopropyl-O-cyanoethyl-O-(di-oleoyl-sn-(2S)-glycerol)phosphonamidite (214422-50-1) + 1D-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol → 1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol (942914-42-3)

Guidance literature:

N,N-diisopropyl-O-cyanoethyl-O-(di-oleoyl-sn-(2S)-glycerol)phosphonamidite; 1D-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol; With 1H-tetrazole; In dichloromethane; at 20 ℃; for 24h;

With tert.-butylhydroperoxide; In dichloromethane; for 1h; Further stages.;

DOI:10.1021/ja070195b

Reference yield:

1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol (942914-42-3) → C53H100O19P2S

Guidance literature:

With bis(trimethylsilyl)trifluoroacetamide; triethylamine; In acetonitrile; at 20 ℃; for 24h;

DOI:10.1021/ja070195b

Reference yield:

1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-O-(cyanoethyl)phospho)-5-(bis(cyanoethyl)phosphothionate)-2,3,4,6-O-tetrakis(methoxymethylene)-myo-inositol (942914-42-3) → 1D-O-(1,2-di-O-oleoyl-sn-glycerol-3-phospho)-5-(phosphothionate)-myo-inositol

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N; bis(trimethylsilyl)trifluoroacetamide / acetonitrile / 24 h / 20 °C

2: trimethylsilyl bromide; bis(trimethylsilyl)trifluoroacetamide / CH₂Cl₂ / 2 h / 20 °C

With bis(trimethylsilyl)trifluoroacetamide; trimethylsilyl bromide; triethylamine; In dichloromethane; acetonitrile;

DOI:10.1021/ja070195b

upstream raw materials:

N,N-diisopropyl-O-cyanoethyl-O-(di-oleoyl-sn-(2S)-glycerol)phosphonamidite