N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate

Base Information

Chemical Name:N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate
CAS No.:1312472-93-7
Molecular Formula:C₂HF₃O₂*C₁₇H₂₅NO
Molecular Weight:373.416
Hs Code.:

Synonyms:N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate

Suppliers and Price of N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate

There total 9 articles about N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1312472-91-5
tert-butyl benzyl(3,3-dimethyl-5-methylene-6-oxoheptyl)carbamate

: 76-05-1
trifluoroacetic acid

: 1312472-93-7
N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/ol201448h

Reference yield:

: 1312472-88-0
1-benzyl-5,5-dimethylazepan-2-one

: 1312472-93-7
N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate

Guidance literature:: Multi-step reaction with 7 steps

1.1: lithium triethylborohydride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 4 h / 20 °C / Inert atmosphere

3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

3.2: -78 - 20 °C / Inert atmosphere

4.1: pyrrolidine; p-N,N-dimethylaminobenzoic acid / dichloromethane; water / 0.25 h / Inert atmosphere; Reflux

5.1: tetrahydrofuran / 0.75 h / -78 - 20 °C / Inert atmosphere

6.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

7.1: dichloromethane / 0.5 h / 20 °C / Inert atmosphere

With pyrrolidine; oxalyl dichloride; sulfur trioxide pyridine complex; p-N,N-dimethylaminobenzoic acid; lithium triethylborohydride; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; water; 3.1: Swern oxidation / 3.2: Swern oxidation;
DOI:10.1021/ol201448h

Reference yield:

: 1312472-90-4
tert-butyl benzyl(5-formyl-3,3-dimethylhex-5-en-1-yl)carbamate

: 1312472-93-7
N-benzyl-3,3-dimethyl-5-methylene-6-oxoheptan-1-aminium 2,2,2-trifluoroacetate

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 0.75 h / -78 - 20 °C / Inert atmosphere

2: sulfur trioxide pyridine complex; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

3: dichloromethane / 0.5 h / 20 °C / Inert atmosphere

With sulfur trioxide pyridine complex; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ol201448h