tert-butyl (2S)-3-[(2S,3R,4R,5R,6R)-4,5-diacetyloxy-6-(acetyloxymethyl)-3-azidooxan-2-yl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate

Base Information

Chemical Name:tert-butyl (2S)-3-[(2S,3R,4R,5R,6R)-4,5-diacetyloxy-6-(acetyloxymethyl)-3-azidooxan-2-yl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate
CAS No.:110797-36-9
Molecular Formula:C₃₄H₄₀N₄O₁₂
Molecular Weight:696.711
Hs Code.:
DSSTox Substance ID:DTXSID101102917
Nikkaji Number:J3.240.128G

tert-butyl (2S)-3-[(2S,3R,4R,5R,6R)-4,5-diacetyloxy-6-(acetyloxymethyl)-3-azidooxan-2-yl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate

Synonyms:110797-36-9;DTXSID101102917;A902332;4-((9H-fluoren-9-yl)methyl) 1-(tert-butyl) (S)-2-((((2S,3R,4R,5R,6R)-4,5,6-triacetoxy-3-azidotetrahydro-2H-pyran-2-yl)oxy)methyl)succinate;N-(9-Fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-desoxy--D-galactopyranosyl)-L-serin-tert-butylester;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-alpha-D-galactopyranosyl)-L-serine 1,1-dimethylethyl ester

Suppliers and Price of tert-butyl (2S)-3-[(2S,3R,4R,5R,6R)-4,5-diacetyloxy-6-(acetyloxymethyl)-3-azidooxan-2-yl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 4 raw suppliers

Chemical Property of tert-butyl (2S)-3-[(2S,3R,4R,5R,6R)-4,5-diacetyloxy-6-(acetyloxymethyl)-3-azidooxan-2-yl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:18
Exact Mass:696.26427272
Heavy Atom Count:50
Complexity:1260

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)OCC1C(C(C(C(O1)OCC(C(=O)OC(C)(C)C)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)N=[N+]=[N-])OC(=O)C)OC(=O)C
Isomeric SMILES:CC(=O)OC[C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)OC[C@@H](C(=O)OC(C)(C)C)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)N=[N+]=[N-])OC(=O)C)OC(=O)C

Technology Process of tert-butyl (2S)-3-[(2S,3R,4R,5R,6R)-4,5-diacetyloxy-6-(acetyloxymethyl)-3-azidooxan-2-yl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate

There total 1 articles about tert-butyl (2S)-3-[(2S,3R,4R,5R,6R)-4,5-diacetyloxy-6-(acetyloxymethyl)-3-azidooxan-2-yl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73724-45-5
N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine

: 110797-36-9
N-(9-Fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-desoxy-α-D-galactopyranosyl)-L-serin-tert-butylester

Guidance literature:: Multi-step reaction with 4 steps

1: NEt₃ / CH₂Cl₂ / 30 h

2: conc.H₂SO₄ / CH₂Cl₂ / 240 h

3: N₂H₄*H₂O / ethanol / 0.5 h

4: 1.) Ag₂CO₃, AgClO₄, molecular sieve / 1.) CH₂Cl₂, toluene, 2 h, RT; 2.) 4 d

With molecular sieve; sulfuric acid; silver perchlorate; hydrazine hydrate; triethylamine; silver carbonate; In ethanol; dichloromethane;

Reference yield:

: 110797-36-9
N-(9-Fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-desoxy-α-D-galactopyranosyl)-L-serin-tert-butylester

: C₃₇H₄₂O₁₀N₂

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid; zinc

2: sodium methylate / methanol / pH 9

3: toluene-4-sulfonic acid

With sodium methylate; toluene-4-sulfonic acid; acetic acid; zinc; In methanol;
DOI:10.1002/ejoc.201100304

Reference yield:

: 110797-36-9
N-(9-Fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-desoxy-α-D-galactopyranosyl)-L-serin-tert-butylester

: C₅₁H₆₀O₁₉N₂

Guidance literature:: Multi-step reaction with 4 steps

1: acetic acid; zinc

2: sodium methylate / methanol / pH 9

3: toluene-4-sulfonic acid

4: mercury(II) cyanide

With sodium methylate; mercury(II) cyanide; toluene-4-sulfonic acid; acetic acid; zinc; In methanol;
DOI:10.1002/ejoc.201100304