1-(Hydroxy1>methyl)-2-methylbenzol

Base Information

• Chemical Name: 1-(Hydroxy1>methyl)-2-methylbenzol
• CAS No.: 127882-45-5
• Molecular Formula: C₈H₁₀O
• Molecular Weight: 123.159
• Mol file: 127882-45-5.mol

Synonyms:1-(Hydroxy1>methyl)-2-methylbenzol

Chemical Property of 1-(Hydroxy1>methyl)-2-methylbenzol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(Hydroxy1>methyl)-2-methylbenzol

There total 2 articles about 1-(Hydroxy1>methyl)-2-methylbenzol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-methylbenzaldehdye-formyl-d1 (34761-85-8) → 1-(Hydroxy1>methyl)-2-methylbenzol (127882-45-5)

Guidance literature:

With hydrogenchloride; hydrogen; bis(acetato){(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl}rutenium(II); In tetrahydrofuran; for 24h; under 8360 Torr; Ambient temperature;

DOI:10.1016/0022-328X(94)87204-X

Reference yield: 89.0%

2-methylphenyl aldehyde (529-20-4) → 1-(Hydroxy1>methyl)-2-methylbenzol (127882-45-5)

Guidance literature:

With lithium aluminium deuteride;

Reference yield: 84.0%

1-(Hydroxy1>methyl)-2-methylbenzol (127882-45-5) → 1-(Bromo1>methyl)-2-methylbenzol (127882-46-6)

Guidance literature:

With phosphorus tribromide; In toluene; at 100 ℃; for 1h;

upstream raw materials:

2-methylphenyl aldehyde

2-methylbenzaldehdye-formyl-d₁

Downstream raw materials:

1-(Bromo1>methyl)-2-methylbenzol