tert-butyl allyl((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate

Base Information

• Chemical Name: tert-butyl allyl((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate
• CAS No.: 1177260-54-6
• Molecular Formula: C₂₈H₃₇NO₄
• Molecular Weight: 451.606
• Mol file: 1177260-54-6.mol

Synonyms:tert-butyl allyl((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate

Chemical Property of tert-butyl allyl((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl allyl((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate

There total 1 articles about tert-butyl allyl((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

tert-butyl ((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate (1177260-52-4) + allyl bromide (106-95-6) → tert-butyl allyl((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate (1177260-54-6)

Guidance literature:

tert-butyl ((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate; With potassium hexamethylsilazane; In N,N-dimethyl-formamide; toluene; at -25 ℃; for 0.166667h; Inert atmosphere;

allyl bromide; In N,N-dimethyl-formamide; toluene; at -25 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/jo901127a

Reference yield:

tert-butyl allyl((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate (1177260-54-6) → C23H29NO2

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1021/jo901127a

upstream raw materials:

tert-butyl ((1R,3S,4R)-3-benzyloxy-4-benzyloxymethylbicyclo[3.1.0]hexan-1-yl)carbamate

allyl bromide