C₁₈H₁₇BrO₅

Base Information

• Chemical Name: C₁₈H₁₇BrO₅
• CAS No.: 1637568-96-7
• Molecular Formula: C₁₈H₁₇BrO₅
• Molecular Weight: 393.234
• Mol file: 1637568-96-7.mol

Synonyms:C₁₈H₁₇BrO₅

Chemical Property of C₁₈H₁₇BrO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₁₇BrO₅

There total 2 articles about C₁₈H₁₇BrO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4,5-trimethoxyphenol (642-71-7) + C9H6BrClO (119411-68-6,851664-10-3) → C18H17BrO5 (1637568-96-7)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; for 0.166667h; Reflux;

DOI:10.1248/cpb.c13-00897

Reference yield:

2-bromocinnamic acid (7345-79-1,20595-39-5,7499-56-1) → C18H17BrO5 (1637568-96-7)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C / Cooling with ice

2: boron trifluoride diethyl etherate / dichloromethane / 0.17 h / Reflux

With oxalyl dichloride; boron trifluoride diethyl etherate; N,N-dimethyl-formamide; In dichloromethane;

DOI:10.1248/cpb.c13-00897

Reference yield: 61.0%

C18H17BrO5 (1637568-96-7) → 2-(2-bromophenyl)-5,6,7-trimethoxy-4H-chromen-4-one (1637568-97-8)

Guidance literature:

With iodine; In dimethyl sulfoxide; for 3h; Reflux;

DOI:10.1248/cpb.c13-00897

upstream raw materials:

2-bromocinnamic acid

3,4,5-trimethoxyphenol

C₉H₆BrClO

Downstream raw materials:

2-(2-bromophenyl)-5,6,7-trimethoxy-4H-chromen-4-one

2-(2-bromophenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one

2-(2-bromophenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one

2-(2-bromophenyl)-5,6,7-trihydroxy-4H-chromen-4-one