(2S,3S,11bR)-8-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2-acetic acid ethyl ester

Base Information

• Chemical Name: (2S,3S,11bR)-8-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo
• Molecular Formula: C₂₈H₃₇NO₅
• Molecular Weight: 467.605

Synonyms:(2S,3S,11bR)-8-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2-acetic acid ethyl ester

Chemical Property of (2S,3S,11bR)-8-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

There total 2 articles about (2S,3S,11bR)-8-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

trans-8-benzyloxy-2-ethoxycarbonylmethyl-3-ethyl-1,2,3,4,6,7-hexahydro-9,10-dimethoxybenzoquinolizinium chloride (73136-35-3) → ethyl (+/-)-8-benzyloxy-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2β-acetate (56774-72-2,57130-35-5,109009-03-2)

Guidance literature:

platinum(IV) oxide; In ethanol; at 20 ℃; for 2h; under 760 Torr;

DOI:10.1016/0040-4020(80)80049-4

Reference yield:

(2S,3S)-8-Benzyloxy-2-ethoxycarbonylmethyl-3-ethyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-pyrido[2,1-a]isoquinolinylium; chloride (56774-71-1,57130-33-3,57130-34-4,73136-35-3) → (2S,3S,11bR)-8-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2-acetic acid ethyl ester (109009-03-2)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; at 22 ℃; for 0.666667h; Yield given;

DOI:10.1248/cpb.34.669

Reference yield: 99.0%

ethyl (+/-)-8-benzyloxy-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2β-acetate (56774-72-2,57130-35-5,109009-03-2) → (+/-)-8-benzyloxy-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2β-acetic acid (61194-41-0,65942-18-9)

Guidance literature:

With sodium hydroxide; In ethanol; at 20 ℃; for 24h;

upstream raw materials:

trans-8-benzyloxy-2-ethoxycarbonylmethyl-3-ethyl-1,2,3,4,6,7-hexahydro-9,10-dimethoxybenzoquinolizinium chloride

(2S,3S)-8-Benzyloxy-2-ethoxycarbonylmethyl-3-ethyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-pyrido[2,1-a]isoquinolinylium; chloride

Downstream raw materials:

(+/-)-8-benzyloxy-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2β-ethanol

(+/-)-8-benzyloxy-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2β-acetic acid

(+/-)-2β-(3,4-dihydro-6-hydroxy-7-methoxy-1-isoquinolyl)methyl-3α-ethyl-1,3,4,6,7,11bα-hexahydro-8-hydroxy-9,10-dimethoxy-2H-benzoquinolizine<(+/-)-alangicine>

(+/-)-8-benzyloxy-2β-(3,4-dihydro-6-hydroxy-7-methoxy-1-isoquinolyl)methyl-3α-ethyl-1,3,4,6,7,11bα-hexahydro-9,10-dimethoxy-2H-benzoquinolizine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 109009-03-2 (2S,3S,11bR)-8-benzyloxy-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-2-acetic acid ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send