C₁₅H₁₅IN₂O

Base Information

• Chemical Name: C₁₅H₁₅IN₂O
• CAS No.: 1443771-22-9
• Molecular Formula: C₁₅H₁₅IN₂O
• Molecular Weight: 366.201
• Mol file: 1443771-22-9.mol

Synonyms:C₁₅H₁₅IN₂O

Chemical Property of C₁₅H₁₅IN₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₅H₁₅IN₂O

There total 2 articles about C₁₅H₁₅IN₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

para-diiodobenzene (624-38-4,1032416-46-8) + pyridine-2-carboxylic acid propylamide (229646-01-9) → C15H15IN2O (1443771-22-9)

Guidance literature:

With phosphoric acid dibenzyl ester; palladium diacetate; silver carbonate; In tert-Amyl alcohol; at 110 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.3762/bjoc.12.119

Reference yield:

N-(3-phenylpropyl)picolinamide → C15H15IN2O (1443771-11-6) + C15H15IN2O (1443771-22-9)

Guidance literature:

With tetrafluoroboric acid diethyl ether; N-iodo-succinimide; In dichloromethane; trifluoroacetic acid; at 0 ℃; Overall yield = 82 %; regioselective reaction; Inert atmosphere;

DOI:10.1021/ol4015078

Reference yield:

C15H15IN2O (1443771-22-9) → C15H14I2N2O

Guidance literature:

With tetrafluoroboric acid diethyl ether; N-iodo-succinimide; trifluoroacetic acid; In dichloromethane; at 0 ℃; for 4h; Inert atmosphere;

DOI:10.3762/bjoc.12.119

upstream raw materials:

para-diiodobenzene

pyridine-2-carboxylic acid propylamide