6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide)

Base Information

• Chemical Name: 6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide)
• CAS No.: 115121-74-9
• Molecular Formula: C₂₂H₁₈N₂O₅
• Molecular Weight: 390.395
• Mol file: 115121-74-9.mol

Synonyms:6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide)

Chemical Property of 6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide)

There total 4 articles about 6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-nitro-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide) (857388-87-5) → 6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide) (115121-74-9)

Guidance literature:

With palladium on activated charcoal; ethanol; at 70 ℃; Hydrogenation;

DOI:10.1021/ja01627a032

Reference yield:

4,5-methylenedioxy-2-nitrobenzoyl chloride (50425-29-1) → 6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide) (115121-74-9)

Guidance literature:

Multi-step reaction with 3 steps

1: dioxane; sodium hydrogencarbonate; water

2: aqueous alkaline solution

3: palladium/charcoal; ethanol / 70 °C / Hydrogenation

With 1,4-dioxane; palladium on activated charcoal; ethanol; alkaline solution; water; sodium hydrogencarbonate;

DOI:10.1021/ja01627a032

Reference yield:

6-nitro-benzo[1,3]dioxole-5-carboxylic acid-(4-hydroxy-N-methyl-anilide) (109411-55-4) → 6-amino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide) (115121-74-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous alkaline solution

2: palladium/charcoal; ethanol / 70 °C / Hydrogenation

With palladium on activated charcoal; ethanol; alkaline solution;

DOI:10.1021/ja01627a032

upstream raw materials:

6-nitro-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide)

4,5-methylenedioxy-2-nitrobenzoyl chloride

6-nitro-benzo[1,3]dioxole-5-carboxylic acid-(4-hydroxy-N-methyl-anilide)

4-(methylamino)phenol sulphate

Downstream raw materials:

6-benzylidenamino-benzo[1,3]dioxole-5-carboxylic acid-(4-benzoyloxy-N-methyl-anilide)