5,6-endo-trimethylene-9-endo-norbornanol tosylate

Base Information

• Chemical Name: 5,6-endo-trimethylene-9-endo-norbornanol tosylate
• CAS No.: 16326-24-2
• Molecular Formula: C₁₇H₂₂O₃S
• Molecular Weight: 306.426
• Mol file: 16326-24-2.mol

Synonyms:5,6-endo-trimethylene-9-endo-norbornanol tosylate

Chemical Property of 5,6-endo-trimethylene-9-endo-norbornanol tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,6-endo-trimethylene-9-endo-norbornanol tosylate

There total 2 articles about 5,6-endo-trimethylene-9-endo-norbornanol tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3aα,7aα)-octahydro-4α,7α-methano-2H-inden-2-one (19138-60-4) → 5,6-endo-trimethylene-9-endo-norbornanol tosylate (16326-24-2)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether / Heating

2: pyridine

With pyridine; lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jo00350a028

Reference yield:

(1RS,2RS,6SR,7RS)-endo-tricyclo<5.2.1.02,6>decan-4-ol (10271-49-5) + p-toluenesulfonyl chloride (98-59-9) → 5,6-endo-trimethylene-9-endo-norbornanol tosylate (16326-24-2)

Guidance literature:

With pyridine;

DOI:10.1021/jo00350a028

Reference yield:

5,6-endo-trimethylene-9-endo-norbornanol tosylate (16326-24-2) → (3aR,4R,7S,7aS)-octahydro-1H-4,7-methanoindene (2825-83-4)

Guidance literature:

Multi-step reaction with 2 steps

1: KI / acetone / 25 °C

2: Zn, AcOH, HCl

With hydrogenchloride; acetic acid; potassium iodide; zinc; In acetone;

DOI:10.1039/j29710001214

upstream raw materials:

(1RS,2RS,6SR,7RS)-endo-tricyclo<5.2.1.0^2,6>decan-4-ol

p-toluenesulfonyl chloride

(3aα,7aα)-octahydro-4α,7α-methano-2H-inden-2-one

Downstream raw materials:

(3aR,4R,7S,7aS)-octahydro-1H-4,7-methanoindene