Technology Process of C15H13F4N5O
There total 8 articles about C15H13F4N5O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C14H14F4N4O; 9-fluorenylmethoxycarbonyl isothiocyanate;
In
acetonitrile;
at 0 ℃;
for 1h;
With
N-ethyl-N,N-diisopropylamine; methyl iodide;
In
acetonitrile;
at 20 - 80 ℃;
for 17h;
With
piperidine;
In
acetonitrile;
at 20 ℃;
for 20h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: ozone / dichloromethane / -78 °C
1.2: 1 h / -78 °C / Inert atmosphere
2.1: hydrogenchloride / methanol; 1,4-dioxane / 2 h / 20 °C
3.1: tetrahydrofuran / 20 h / 20 - 60 °C
4.1: N,N-dimethyl-formamide / 5 h / 80 °C
5.1: hydrazinium monoacetate / ethanol / 1 h / Reflux
6.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
7.1: acetonitrile / 1 h / 0 °C
7.2: 17 h / 20 - 80 °C
7.3: 20 h / 20 °C
With
hydrogenchloride; hydrazinium monoacetate; ozone; trifluoroacetic acid;
In
tetrahydrofuran; 1,4-dioxane; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrazinium monoacetate / ethanol / 1 h / Reflux
2.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
3.1: acetonitrile / 1 h / 0 °C
3.2: 17 h / 20 - 80 °C
3.3: 20 h / 20 °C
With
hydrazinium monoacetate; trifluoroacetic acid;
In
ethanol; dichloromethane; acetonitrile;