C₂₉H₂₄Cl₅N₃O₆

Base Information

• Chemical Name: C₂₉H₂₄Cl₅N₃O₆
• CAS No.: 1382529-24-9
• Molecular Formula: C₂₉H₂₄Cl₅N₃O₆
• Molecular Weight: 687.791
• Mol file: 1382529-24-9.mol

Synonyms:C₂₉H₂₄Cl₅N₃O₆

Chemical Property of C₂₉H₂₄Cl₅N₃O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₂₄Cl₅N₃O₆

There total 3 articles about C₂₉H₂₄Cl₅N₃O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

methyl N-(2,6-dichlorobenzoyl)-3-iodo-L-tyrosinate (959991-75-4) + C12H11Cl3N2O2 (1382529-23-8) → C29H24Cl5N3O6 (1382529-24-9)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 65 ℃;

DOI:10.1016/j.bmcl.2012.04.061

Reference yield:

2-aminopyridine (504-29-0) → C29H24Cl5N3O6 (1382529-24-9)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: di-tert-butyl-diazodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C

3: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 65 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; di-tert-butyl-diazodicarboxylate; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 2: Mitsunobu reaction;

DOI:10.1016/j.bmcl.2012.04.061

Reference yield:

methyl N-(2,6-dichlorobenzoyl)-L-tyrosinate (938195-80-3) → C29H24Cl5N3O6 (1382529-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N,N-trimethylbenzenemethanaminium dichloroiodate / N,N-dimethyl-formamide / 0 - 20 °C

2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide / 65 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N,N,N-trimethylbenzenemethanaminium dichloroiodate; triethylamine; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2012.04.061

upstream raw materials:

2-aminopyridine

methyl N-(2,6-dichlorobenzoyl)-L-tyrosinate

methyl N-(2,6-dichlorobenzoyl)-3-iodo-L-tyrosinate

C₁₂H₁₁Cl₃N₂O₂

Downstream raw materials:

C₂₆H₂₃Cl₂N₃O₄