1-(tert-butoxycarbonyl)-2-[(2E)-12-{[tert-butyl(diphenyl)silyl]oxy}-dodec-2-enyl]-L-proline

Base Information

• Chemical Name: 1-(tert-butoxycarbonyl)-2-[(2E)-12-{[tert-butyl(diphenyl)silyl]oxy}-dodec-2-enyl]-L-proline
• CAS No.: 1044140-52-4
• Molecular Formula: C₃₈H₅₇NO₅Si
• Molecular Weight: 635.96
• Mol file: 1044140-52-4.mol

Synonyms:1-(tert-butoxycarbonyl)-2-[(2E)-12-{[tert-butyl(diphenyl)silyl]oxy}-dodec-2-enyl]-L-proline

Chemical Property of 1-(tert-butoxycarbonyl)-2-[(2E)-12-{[tert-butyl(diphenyl)silyl]oxy}-dodec-2-enyl]-L-proline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(tert-butoxycarbonyl)-2-[(2E)-12-{[tert-butyl(diphenyl)silyl]oxy}-dodec-2-enyl]-L-proline

There total 1 articles about 1-(tert-butoxycarbonyl)-2-[(2E)-12-{[tert-butyl(diphenyl)silyl]oxy}-dodec-2-enyl]-L-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

N-tert-butoxycarbonyl-L-α-allylproline (144085-23-4) + 11-[((1,1-dimethylethyl)diphenylsilicon)oxy]-1-undecene → 1-(tert-butoxycarbonyl)-2-[(2E)-12-{[tert-butyl(diphenyl)silyl]oxy}-dodec-2-enyl]-L-proline (1044140-52-4)

Guidance literature:

With dichloro(tricyclohexylphosphino)(benzylidene)(1,3-dimesityl-4,5-dihydroimidazol-2-ylidene)ruthenium(III); In dichloromethane; at 80 ℃; for 0.666667h; Microwave irradiation; Cooling;

DOI:10.1002/ejoc.200800044

Reference yield: 82.0%

1-(tert-butoxycarbonyl)-2-[(2E)-12-{[tert-butyl(diphenyl)silyl]oxy}-dodec-2-enyl]-L-proline (1044140-52-4) → 1-(tert-butoxycarbonyl)-2-(12-{[tert-butyl(diphenyl)silyl]oxy}dodecyl)-L-proline (1044140-64-8)

Guidance literature:

With Pd(OH)2/C; hydrogen; In methanol; under 760.051 Torr;

DOI:10.1002/ejoc.200800044

upstream raw materials:

N-tert-butoxycarbonyl-L-α-allylproline

Downstream raw materials:

1-(tert-butoxycarbonyl)-2-(12-{[tert-butyl(diphenyl)silyl]oxy}dodecyl)-L-proline