Moricizine

Base Information

Chemical Name:Moricizine
CAS No.:31883-05-3
Molecular Formula:C22H25 N3 O4 S
Molecular Weight:427.524
Hs Code.:2934999090
European Community (EC) Number:250-854-5
UNII:2GT1D0TMX1
DSSTox Substance ID:DTXSID4023335
Nikkaji Number:J19.957E
Wikipedia:Moracizine
Wikidata:Q904071
NCI Thesaurus Code:C66196
Pharos Ligand ID:GGCMNFLZQF58
Metabolomics Workbench ID:42995
ChEMBL ID:CHEMBL1075
Mol file:31883-05-3.mol

Synonyms:EN 313;EN-313;EN313;Ethmozin;Ethmozine;Etmozin;Hydrochloride, Moricizine;Moracizin;Moracizine;Moricizine;Moricizine Hydrochloride

Suppliers and Price of Moricizine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Moricizine
1mg
$ 403.00

TRC
Moricizine
10mg
$ 110.00

Medical Isotopes, Inc.
Moricizine
100 mg
$ 2800.00

American Custom Chemicals Corporation
MORICIZINE 95.00%
100MG
$ 1732.50

American Custom Chemicals Corporation
MORICIZINE 95.00%
10MG
$ 214.20

Total 44 raw suppliers

Chemical Property of Moricizine

Chemical Property:

Vapor Pressure:1.54E-15mmHg at 25°C
Melting Point:156-157°
Boiling Point:625oC at 760 mmHg
PKA:6.4(at 25℃)
Flash Point:331.8oC
PSA：96.41000
Density:1.315g/cm3
LogP:4.18250
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Very Slightly)
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:427.15657746
Heavy Atom Count:30
Complexity:601

Purity/Quality:

97% ^*data from raw suppliers

Moricizine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NC1=CC2=C(C=C1)SC3=CC=CC=C3N2C(=O)CCN4CCOCC4
Recent ClinicalTrials:Cardiac Arrhythmia Suppression Trial (CAST)
Uses Cardiac depressant (anti-arrhythmic). Moricizine, is Phenothiazine (P318040) derivative, which It was used as an Antiarrhythmic agent. It is also shown that moracizine is effective in suppressing premature ventricular contractions, couplets, and nonsustained ventricular tachycardia.
Therapeutic Function Antiarrhythmic
Clinical Use Moricizine (Ethmozine) is an antiarrhythmic used to treat documented life-threatening arrhythmias. Moricizine is indicated for the treatment of documented ventricular arrhythmias, particularly sustained ventricular tachycardia. Moricizine was evaluated in the CAST II clinical trial for the prevention of postinfarction ventricular premature complexes. It was ineffective and found to be proarrhythmic. Patients in the moricizine arm of the trial exhibited a greater incidence of sudden cardiac death than did controls.
Drug interactions Clinically significant interactions with moricizine do not appear to exist.

Technology Process of Moricizine

There total 1 articles about Moricizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: