6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol

Base Information

• Chemical Name: 6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol
• CAS No.: 1336875-65-0
• Molecular Formula: C₆₂H₈₄O₁₃Si₂
• Molecular Weight: 1093.51
• Mol file: 1336875-65-0.mol

Synonyms:6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol

Chemical Property of 6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol

There total 1 articles about 6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

C36H34Cl3NO8 + 3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-(L-1,7,7-trimethyl<2.2.1>bicyclohept-6-ylidene)-D-myo-inositol → 6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol (1336875-65-0)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In diethyl ether; at -70 ℃; for 0.75h; Molecular sieve;

DOI:10.1021/jm2008419

Reference yield: 78.0%

6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol (1336875-65-0) → 6-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol (1336875-66-1)

Guidance literature:

With sodium methylate; In methanol; dichloromethane; for 22h;

DOI:10.1021/jm2008419

Reference yield:

6-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol (1336875-65-0) → 3,4,5-tri-O-benzyl-6-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1,2-O-((1S,4S)-1,7,7-trimethyl[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol (1336875-68-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium methylate / methanol; dichloromethane / 22 h

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h

3: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C

With tetrabutyl ammonium fluoride; sodium methylate; sodium hydride; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;

DOI:10.1021/jm2008419

Downstream raw materials:

3,4,5-tri-O-benzyl-6-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1,2-O-((1S,4S)-1,7,7-trimethyl[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol

6-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-3,4-O-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)-1,2-O-((1S,4S)-1,7,7-trimethyl-[2.2.1]bicyclohept-6-ylidene)-D-myo-inositol

C₄₃H₅₄O₁₁